This assisted reproduction technique is applied in cases where the cause of the sterility is a low ova count or an absence of ova (premature ovarian failure, menopause or absence of ovaries as a result of surgery) or in cases where pregnancy with the ova of the woman is not recommended basically for genetic reasons.

The main difference from the donation of semen is that ova cannot be frozen. Consequently, the ova are donated while fresh, synchronising the menstrual cycles of the donor and the patient.

The legal requirements for donating ova are as follows: To be between 18 and 35 years of age, have good mental and physical health, have a negative serological analysis for HIV, hepatitis B and C, syphilis, etc. and not have a personal or family record of genetic or hereditary diseases.

Obviously, the donation is always anonymous, confidential and secret. This means that neither the donor nor the patient can know the other's identity nor provide or choose a donor. In addition, as it is a donation, no economic payment is made for the donated ova but payment is given for the trouble taken, travel to the clinic, the stay at the clinic and the time dedicated to the donation.

Once the donor has been accepted, it is the responsibility of the medical staff to ensure that the donor is as phenotypically and immunologically similar to the patient as possible.